<h2 data-start="213" data-end="224">GHK-Cu</h2>
<p data-start="225" data-end="260"><strong data-start="225" data-end="260">Synthetic Peptide Research Tool</strong></p>
<p data-start="262" data-end="514">GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a <strong data-start="318" data-end="365">synthetic tripeptide conjugated with copper</strong>, widely utilized in laboratory and preclinical studies to investigate <strong data-start="436" data-end="511">cellular signaling, extracellular matrix regulation, and tissue biology</strong>.</p>
<p data-start="516" data-end="861">Preclinical research explores GHK-Cu as a <strong data-start="558" data-end="680">modulator of molecular pathways associated with metal ion-dependent signaling, gene expression, and enzymatic activity</strong>. Investigations typically focus on <strong data-start="716" data-end="819">cellular repair models, matrix metalloproteinase regulation, and oxidative stress-related signaling</strong>, without implying therapeutic outcomes.</p>
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<h2 data-start="868" data-end="909">Peptide Identity and Molecular Profile</h2>
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<th data-start="911" data-end="922" data-col-size="sm">Property</th>
<th data-start="922" data-end="937" data-col-size="md">Description</th>
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<td data-start="965" data-end="980" data-col-size="sm">Peptide Name</td>
<td data-start="980" data-end="990" data-col-size="md">GHK-Cu</td>
</tr>
<tr data-start="991" data-end="1045">
<td data-start="991" data-end="1007" data-col-size="sm">Peptide Class</td>
<td data-col-size="md" data-start="1007" data-end="1045">Synthetic tripeptide–metal complex</td>
</tr>
<tr data-start="1046" data-end="1099">
<td data-start="1046" data-end="1066" data-col-size="sm">Amino Acid Length</td>
<td data-col-size="md" data-start="1066" data-end="1099">3 residues (copper-complexed)</td>
</tr>
<tr data-start="1100" data-end="1139">
<td data-start="1100" data-end="1119" data-col-size="sm">Peptide Sequence</td>
<td data-col-size="md" data-start="1119" data-end="1139">Gly-His-Lys-Cu²⁺</td>
</tr>
<tr data-start="1140" data-end="1192">
<td data-start="1140" data-end="1159" data-col-size="sm">Molecular Weight</td>
<td data-start="1159" data-end="1192" data-col-size="md">~404 Da, copper‑complexed form</td>
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<tr data-start="1193" data-end="1280">
<td data-start="1193" data-end="1213" data-col-size="sm">Biological Origin</td>
<td data-col-size="md" data-start="1213" data-end="1280">Synthetic analog of naturally occurring human plasma tripeptide</td>
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<h2 data-start="1287" data-end="1323">Chemical and Registry Information</h2>
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<th data-start="1325" data-end="1336" data-col-size="sm">Property</th>
<th data-start="1336" data-end="1345" data-col-size="md">Value</th>
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<td data-start="1367" data-end="1387" data-col-size="sm">Molecular Formula</td>
<td data-col-size="md" data-start="1387" data-end="1403">C₁₄H₂₄N₆O₄Cu</td>
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<tr data-start="1404" data-end="1431">
<td data-start="1404" data-end="1417" data-col-size="sm">CAS Number</td>
<td data-col-size="md" data-start="1417" data-end="1431">49557-75-7</td>
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<tr data-start="1432" data-end="1457">
<td data-start="1432" data-end="1446" data-col-size="sm">PubChem CID</td>
<td data-start="1446" data-end="1457" data-col-size="md">5281809</td>
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<td data-start="1458" data-end="1469" data-col-size="sm">Synonyms</td>
<td data-start="1469" data-end="1522" data-col-size="md">GHK-Cu, Glycyl-L-Histidyl-L-Lysine copper complex</td>
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<td data-start="1523" data-end="1538" data-col-size="sm">Source Notes</td>
<td data-col-size="md" data-start="1538" data-end="1586">Laboratory-grade, synthetic research peptide</td>
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<h2 data-start="1593" data-end="1646">Biological Pathways Studied (Preclinical Research)</h2>
<p data-start="1648" data-end="1802">In preclinical and in vitro studies, GHK-Cu has been investigated for its interactions with <strong data-start="1740" data-end="1801">cellular regulatory and metal-dependent signaling systems</strong>:</p>
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<th data-start="1804" data-end="1823" data-col-size="sm">Pathway / System</th>
<th data-start="1823" data-end="1843" data-col-size="lg">Research Context</th>
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<td data-start="1882" data-end="1916" data-col-size="sm">Extracellular Matrix Modulation</td>
<td data-col-size="lg" data-start="1916" data-end="1993">Studied for influence on collagen, elastin, and matrix metalloproteinases</td>
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<tr data-start="1994" data-end="2102">
<td data-start="1994" data-end="2023" data-col-size="sm">Copper-Dependent Signaling</td>
<td data-col-size="lg" data-start="2023" data-end="2102">Explored as a metal-peptide complex influencing enzymatic cofactor activity</td>
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<tr data-start="2103" data-end="2216">
<td data-start="2103" data-end="2130" data-col-size="sm">Cellular Stress Response</td>
<td data-col-size="lg" data-start="2130" data-end="2216">Investigated for gene expression changes associated with oxidative stress pathways</td>
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<tr data-start="2217" data-end="2340">
<td data-start="2217" data-end="2253" data-col-size="sm">Tissue Remodeling &amp; Repair Models</td>
<td data-col-size="lg" data-start="2253" data-end="2340">Studied in fibroblast and epithelial cell models to assess matrix-related signaling</td>
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<tr data-start="2341" data-end="2485">
<td data-start="2341" data-end="2368" data-col-size="sm">Gene Regulation Networks</td>
<td data-col-size="lg" data-start="2368" data-end="2485">Examined for transcriptional modulation of genes involved in proliferation, differentiation, and tissue structure</td>
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<h2 data-start="2492" data-end="2516">Research Applications</h2>
<p data-start="2518" data-end="2573">GHK-Cu is commonly employed in laboratory research for:</p>
<ul data-start="2575" data-end="2912">
<li data-start="2575" data-end="2647">
<p data-start="2577" data-end="2647">Preclinical <strong data-start="2589" data-end="2645">extracellular matrix and collagen regulation studies</strong></p>
</li>
<li data-start="2648" data-end="2710">
<p data-start="2650" data-end="2710">Cellular assays for <strong data-start="2670" data-end="2708">metal-dependent enzymatic activity</strong></p>
</li>
<li data-start="2711" data-end="2769">
<p data-start="2713" data-end="2769">Fibroblast and epithelial <strong data-start="2739" data-end="2767">tissue remodeling models</strong></p>
</li>
<li data-start="2770" data-end="2835">
<p data-start="2772" data-end="2835">Investigations of <strong data-start="2790" data-end="2833">gene expression and regulatory networks</strong></p>
</li>
<li data-start="2836" data-end="2912">
<p data-start="2838" data-end="2912">In vitro studies of <strong data-start="2858" data-end="2910">oxidative stress response and cellular signaling</strong></p>
</li>
</ul>
<p data-start="2914" data-end="3064"><strong data-start="2914" data-end="2923">Note:</strong> All applications are restricted to <strong data-start="2959" data-end="3005">preclinical research and laboratory models</strong>. GHK-Cu is <strong data-start="3017" data-end="3061">not intended for human or veterinary use</strong>.</p>
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<h2 data-start="3071" data-end="3105">Storage and Handling Guidelines</h2>
<p data-start="3107" data-end="3321">Store GHK-Cu in a <strong data-start="3125" data-end="3144">cool, dry place</strong>, protected from light and moisture. Maintain standard laboratory storage conditions to preserve peptide stability. Handle using <strong data-start="3273" data-end="3318">institutional laboratory safety protocols</strong>.</p>
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<h2 data-start="3328" data-end="3349">Lyophilized Powder</h2>
<p data-start="3351" data-end="3622">GHK-Cu is supplied as a <strong data-start="3375" data-end="3397">lyophilized powder</strong>, produced through freeze-drying to minimize residual moisture while preserving peptide conformation and metal complex integrity. This format supports <strong data-start="3548" data-end="3594">precise quantification and reproducibility</strong> in experimental settings.</p>
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<h2 data-start="3629" data-end="3663">Shelf Life After Reconstitution</h2>
<p data-start="3665" data-end="4039">Once reconstituted, GHK-Cu no longer retains the dry-state stability. Reconstituted material is generally suitable for <strong data-start="3784" data-end="3813">short-term laboratory use</strong>, with stability influenced by solvent choice, storage temperature, and handling conditions. Laboratory planning should consider <strong data-start="3942" data-end="3975">post-reconstitution stability</strong> as part of experimental design and data integrity management.</p>
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<h3 data-start="4046" data-end="4067">Compliance Notice</h3>
<p data-start="4069" data-end="4335">GHK-Cu is supplied <strong data-start="4088" data-end="4152">exclusively for laboratory and preclinical research purposes</strong>. It is <strong data-start="4160" data-end="4239">not intended for human, therapeutic, veterinary, or diagnostic applications</strong>. All handling must adhere to applicable <strong data-start="4280" data-end="4332">regulatory, institutional, and safety guidelines</strong>.</p>


GHK-Cu

<p>GHK-Cu (Copper Peptide) may support skin health, wound healing, and anti-aging benefits.</p>
